Interactions with articulated objects are a challenging but important task for mobile robots. To tackle this challenge, we propose a novel closed-loop control pipeline, which integrates manipulation priors from affordance estimation with sampling-based whole-body control. We introduce the concept of agent-aware affordances which fully reflect the agent's capabilities and embodiment and we show that they outperform their state-of-the-art counterparts which are only conditioned on the end-effector geometry. Additionally, closed-loop affordance inference is found to allow the agent to divide a task into multiple non-continuous motions and recover from failure and unexpected states. Finally, the pipeline is able to perform long-horizon mobile manipulation tasks, i.e. opening and closing an oven, in the real world with high success rates (opening: 71%, closing: 72%).

Predicting the physical interaction of proteins is a cornerstone problem in computational biology. New classes of learning-based algorithms are actively being developed, and are typically trained end-to-end on protein complex structures extracted from the Protein Data Bank. These training datasets tend to be large and difficult to use for prototyping and, unlike image or natural language datasets, they are not easily interpretable by non-experts. We present Dock2D-IP and Dock2D-IF, two "toy" datasets that can be used to select algorithms predicting protein-protein interactions$\unicode{x2014}$or any other type of molecular interactions. Using two-dimensional shapes as input, each example from Dock2D-IP ("interaction pose") describes the interaction pose of two shapes known to interact and each example from Dock2D-IF ("interaction fact") describes whether two shapes form a stable complex or not. We propose a number of baseline solutions to the problem and show that the same underlying energy function can be learned either by solving the interaction pose task (formulated as an energy-minimization "docking" problem) or the fact-of-interaction task (formulated as a binding free energy estimation problem).